Filling and closing machine from Bosch honored with Red Dot Award

Flexible aseptic parts changeover

The close exchange with customers, as well as their feedback made it possible to add new features to the AFG. For instance, pharmaceutical manufacturers can now also aseptically incorporate powder-handling parts before the start of production with closed RABS (Restricted Access Barrier System). The parts are introduced via transfer lock and then mounted with the aid of gloves. "Parts handling is usually a complicated process," Bandtel explained. "This is why the product-handling parts of the AFG 5000 are light-weighted and easy to handle, so employees can install them with little effort. Thanks to the vertical, ergonomically accessible design, the system can be operated completely from one side." Alternatively, operators can exchange parts when the RABS is open and then sterilize the assembled essential parts with a CIP/SIP process.

Continuous gas flushing reduces residual oxygen

To increase pharmaceutical products’ durability, manufacturers must keep the residual oxygen content in the vial as low as possible. Hence the glass containers are gassed with nitrogen prior to closing. "However, when nitrogen is rapidly and forcefully blown into the vial, there is a risk of powder particles whirling up and out of the vial," Bandtel explained. "We prevent this risk by integrating the gassing channels of the AFG 5000 directly into the stoppering wheel." The rotation of the wheel creates a continuous flow of nitrogen at the bottle opening right up to closing and ensures consistently low residual oxygen levels. "The continuous transportation of the vials within the gassing area optimally supports this process," said Bandtel. "This way, the functionalities of the machine complement each other even more effectively."

Source: Bosh